Cellular Technology Ltd. was formed in 1998 by Dr. Paul V. Lehmann, a Professor at the Case Western Reserve University School of Medicine.
Dr. Lehmann is a leader in the field of T cell immunology with over 20 high ranking publications dedicated to establishing the scientific basis of cytokine ELISPOT analysis.
Dr. Lehmann developed the original ImmunoSpot technology in order to conduct his own research more effectively. The ImmunoSpot platform is the most frequently referenced in the scientific literature in this field and is widely accepted to be the gold standard. Applications of ImmunoSpot technology include diagnosis and drug discovery for infectious diseases such as HIV and tuberculosis, better understanding and treatment of allergies and autoimmunity, the ability to predict rejection/acceptance responses in organ transplantation and significant improvements in vaccine development and monitoring including for various cancers where post treatment monitoring will be a key part of the therapy.
Dr. Lehmann pioneered the development of tools to accurately and reproducibly measure T cell responses. Dr. Lehmann and CTL designed and constructed the world’s very first ELISPOT reader under US Patent No: 6,410,252 (Methods for Measuring T Cell Cytokines, issued June 25, 2002). The company has been at the forefront of this field ever since.
In 2001, CTL established a laboratory to provide assay services to companies and academic researchers involved in cellular immunology research, drug discovery and drug development. These services include immunogenicity testing, plate scanning and analysis, and ELISPOT assay training.
Within recent years, CTL has expanded its platform to include additional products and services for those in the scientific community. These include cryopreserved PBMC, serum-free media, plaque and colony counters, and expanded contract research services.
Headquartered in Cleveland, Ohio, CTL has expanded to include offices in China, Germany, and Japan.